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mac2 gal 3 expression  (Galectin Therapeutics)

 
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    Structured Review

    Galectin Therapeutics mac2 gal 3 expression
    Western blot analysis of inflammatory and structural protein expression. a Representative western <t>blot</t> <t>showing</t> <t>Galectin-3/Mac2</t> <t>(Gal-3)</t> expression in aortic tissue at 2 weeks (2 W) and 4 weeks (4 W) post-intervention versus control. b Quantification of Gal-3 levels reveals significant upregulation at 2 W (46.55 ± 7.31%) and 4 W (87.22 ± 11.14%) compared to control (18.86 ± 10.37%; p < 0.001). c WB showing α-smooth-muscle-actin (α-SMA) expression in the same groups. d Quantification shows reduced α-SMA expression at 2 W (52.79 ± 14.99%) and 4 W (39.16 ± 17.52%) versus control (80.94 ± 14.26%; p = 0.005 and p < 0.001, respectively). Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: ** p < 0.01, *** p < 0.001. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3
    Mac2 Gal 3 Expression, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mac2+gal+3+expression/pmc12834893-168-16-16?v=Galectin+Therapeutics
    Average 86 stars, based on 1 article reviews
    mac2 gal 3 expression - by Bioz Stars, 2026-07
    86/100 stars

    Images

    1) Product Images from "An endovascular porcine model of abdominal aortic aneurysm for interventional radiology research"

    Article Title: An endovascular porcine model of abdominal aortic aneurysm for interventional radiology research

    Journal: European Radiology Experimental

    doi: 10.1186/s41747-025-00673-z

    Western blot analysis of inflammatory and structural protein expression. a Representative western blot showing Galectin-3/Mac2 (Gal-3) expression in aortic tissue at 2 weeks (2 W) and 4 weeks (4 W) post-intervention versus control. b Quantification of Gal-3 levels reveals significant upregulation at 2 W (46.55 ± 7.31%) and 4 W (87.22 ± 11.14%) compared to control (18.86 ± 10.37%; p < 0.001). c WB showing α-smooth-muscle-actin (α-SMA) expression in the same groups. d Quantification shows reduced α-SMA expression at 2 W (52.79 ± 14.99%) and 4 W (39.16 ± 17.52%) versus control (80.94 ± 14.26%; p = 0.005 and p < 0.001, respectively). Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: ** p < 0.01, *** p < 0.001. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3
    Figure Legend Snippet: Western blot analysis of inflammatory and structural protein expression. a Representative western blot showing Galectin-3/Mac2 (Gal-3) expression in aortic tissue at 2 weeks (2 W) and 4 weeks (4 W) post-intervention versus control. b Quantification of Gal-3 levels reveals significant upregulation at 2 W (46.55 ± 7.31%) and 4 W (87.22 ± 11.14%) compared to control (18.86 ± 10.37%; p < 0.001). c WB showing α-smooth-muscle-actin (α-SMA) expression in the same groups. d Quantification shows reduced α-SMA expression at 2 W (52.79 ± 14.99%) and 4 W (39.16 ± 17.52%) versus control (80.94 ± 14.26%; p = 0.005 and p < 0.001, respectively). Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: ** p < 0.01, *** p < 0.001. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3

    Techniques Used: Western Blot, Expressing, Control

    Immunofluorescence analysis of macrophage infiltration and vascular smooth muscle cell loss. a Representative images of aortic tissue stained for Galectin-3 (Gal-3, magenta), α-smooth-muscle-actin (α-SMA; magenta), and DAPI (blue), in control, 2 weeks (2 W), and 4 weeks (4 W) post-intervention samples. Scale bars: 500 µm. b Gal-3-positive area increased significantly at 2 W (15.12 ± 3.88%) and 4 W (16.65 ± 5.27%) versus control (0.66 ± 0.27%; p = 0.012, and p = 0.021, respectively). c α-SMA-positive area decreased at 2 W (3.09 ± 0.70%) and 4 W (2.04 ± 1.43%) versus control (35.18 ± 5.15%; p = 0.003 for both comparisons). Quantified with Keyence Hybrid Cell Count (autothreshold; Version 2.1.1, Keyence Corp.), values signify positive area fraction. Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: * p < 0.05, ** p < 0.01. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3
    Figure Legend Snippet: Immunofluorescence analysis of macrophage infiltration and vascular smooth muscle cell loss. a Representative images of aortic tissue stained for Galectin-3 (Gal-3, magenta), α-smooth-muscle-actin (α-SMA; magenta), and DAPI (blue), in control, 2 weeks (2 W), and 4 weeks (4 W) post-intervention samples. Scale bars: 500 µm. b Gal-3-positive area increased significantly at 2 W (15.12 ± 3.88%) and 4 W (16.65 ± 5.27%) versus control (0.66 ± 0.27%; p = 0.012, and p = 0.021, respectively). c α-SMA-positive area decreased at 2 W (3.09 ± 0.70%) and 4 W (2.04 ± 1.43%) versus control (35.18 ± 5.15%; p = 0.003 for both comparisons). Quantified with Keyence Hybrid Cell Count (autothreshold; Version 2.1.1, Keyence Corp.), values signify positive area fraction. Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: * p < 0.05, ** p < 0.01. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3

    Techniques Used: Immunofluorescence, Staining, Control, Cell Characterization



    Similar Products

    mac2 gal 3 expression  (Galectin Therapeutics)
    86
    Galectin Therapeutics mac2 gal 3 expression
    Western blot analysis of inflammatory and structural protein expression. a Representative western <t>blot</t> <t>showing</t> <t>Galectin-3/Mac2</t> <t>(Gal-3)</t> expression in aortic tissue at 2 weeks (2 W) and 4 weeks (4 W) post-intervention versus control. b Quantification of Gal-3 levels reveals significant upregulation at 2 W (46.55 ± 7.31%) and 4 W (87.22 ± 11.14%) compared to control (18.86 ± 10.37%; p < 0.001). c WB showing α-smooth-muscle-actin (α-SMA) expression in the same groups. d Quantification shows reduced α-SMA expression at 2 W (52.79 ± 14.99%) and 4 W (39.16 ± 17.52%) versus control (80.94 ± 14.26%; p = 0.005 and p < 0.001, respectively). Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: ** p < 0.01, *** p < 0.001. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3
    Mac2 Gal 3 Expression, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mac2+gal+3+expression/pmc12834893-168-16-16?v=Galectin+Therapeutics
    Average 86 stars, based on 1 article reviews
    mac2 gal 3 expression - by Bioz Stars, 2026-07
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Western blot analysis of inflammatory and structural protein expression. a Representative western blot showing Galectin-3/Mac2 (Gal-3) expression in aortic tissue at 2 weeks (2 W) and 4 weeks (4 W) post-intervention versus control. b Quantification of Gal-3 levels reveals significant upregulation at 2 W (46.55 ± 7.31%) and 4 W (87.22 ± 11.14%) compared to control (18.86 ± 10.37%; p < 0.001). c WB showing α-smooth-muscle-actin (α-SMA) expression in the same groups. d Quantification shows reduced α-SMA expression at 2 W (52.79 ± 14.99%) and 4 W (39.16 ± 17.52%) versus control (80.94 ± 14.26%; p = 0.005 and p < 0.001, respectively). Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: ** p < 0.01, *** p < 0.001. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3

    Journal: European Radiology Experimental

    Article Title: An endovascular porcine model of abdominal aortic aneurysm for interventional radiology research

    doi: 10.1186/s41747-025-00673-z

    Figure Lengend Snippet: Western blot analysis of inflammatory and structural protein expression. a Representative western blot showing Galectin-3/Mac2 (Gal-3) expression in aortic tissue at 2 weeks (2 W) and 4 weeks (4 W) post-intervention versus control. b Quantification of Gal-3 levels reveals significant upregulation at 2 W (46.55 ± 7.31%) and 4 W (87.22 ± 11.14%) compared to control (18.86 ± 10.37%; p < 0.001). c WB showing α-smooth-muscle-actin (α-SMA) expression in the same groups. d Quantification shows reduced α-SMA expression at 2 W (52.79 ± 14.99%) and 4 W (39.16 ± 17.52%) versus control (80.94 ± 14.26%; p = 0.005 and p < 0.001, respectively). Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: ** p < 0.01, *** p < 0.001. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3

    Article Snippet: Fig. 6 Western blot analysis of inflammatory and structural protein expression. a Representative western blot showing Galectin-3/Mac2 (Gal-3) expression in aortic tissue at 2 weeks (2 W) and 4 weeks (4 W) post-intervention versus control. b Quantification of Gal-3 levels reveals significant upregulation at 2 W (46.55 ± 7.31%) and 4 W (87.22 ± 11.14%) compared to control (18.86 ± 10.37%; p < 0.001). c WB showing α-smooth-muscle-actin (α-SMA) expression in the same groups. d Quantification shows reduced α-SMA expression at 2 W (52.79 ± 14.99%) and 4 W (39.16 ± 17.52%) versus control (80.94 ± 14.26%; p = 0.005 and p < 0.001, respectively).

    Techniques: Western Blot, Expressing, Control

    Immunofluorescence analysis of macrophage infiltration and vascular smooth muscle cell loss. a Representative images of aortic tissue stained for Galectin-3 (Gal-3, magenta), α-smooth-muscle-actin (α-SMA; magenta), and DAPI (blue), in control, 2 weeks (2 W), and 4 weeks (4 W) post-intervention samples. Scale bars: 500 µm. b Gal-3-positive area increased significantly at 2 W (15.12 ± 3.88%) and 4 W (16.65 ± 5.27%) versus control (0.66 ± 0.27%; p = 0.012, and p = 0.021, respectively). c α-SMA-positive area decreased at 2 W (3.09 ± 0.70%) and 4 W (2.04 ± 1.43%) versus control (35.18 ± 5.15%; p = 0.003 for both comparisons). Quantified with Keyence Hybrid Cell Count (autothreshold; Version 2.1.1, Keyence Corp.), values signify positive area fraction. Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: * p < 0.05, ** p < 0.01. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3

    Journal: European Radiology Experimental

    Article Title: An endovascular porcine model of abdominal aortic aneurysm for interventional radiology research

    doi: 10.1186/s41747-025-00673-z

    Figure Lengend Snippet: Immunofluorescence analysis of macrophage infiltration and vascular smooth muscle cell loss. a Representative images of aortic tissue stained for Galectin-3 (Gal-3, magenta), α-smooth-muscle-actin (α-SMA; magenta), and DAPI (blue), in control, 2 weeks (2 W), and 4 weeks (4 W) post-intervention samples. Scale bars: 500 µm. b Gal-3-positive area increased significantly at 2 W (15.12 ± 3.88%) and 4 W (16.65 ± 5.27%) versus control (0.66 ± 0.27%; p = 0.012, and p = 0.021, respectively). c α-SMA-positive area decreased at 2 W (3.09 ± 0.70%) and 4 W (2.04 ± 1.43%) versus control (35.18 ± 5.15%; p = 0.003 for both comparisons). Quantified with Keyence Hybrid Cell Count (autothreshold; Version 2.1.1, Keyence Corp.), values signify positive area fraction. Individual values: n = 4 for 2 W (dots); n = 4 for 4 W (squares); n = 4 for controls (triangles). Statistical significance: * p < 0.05, ** p < 0.01. 2 W, Two weeks; 4 W, Four weeks; α-SMA, α-smooth-muscle-actin; Gal-3, Galectin-3

    Article Snippet: Fig. 6 Western blot analysis of inflammatory and structural protein expression. a Representative western blot showing Galectin-3/Mac2 (Gal-3) expression in aortic tissue at 2 weeks (2 W) and 4 weeks (4 W) post-intervention versus control. b Quantification of Gal-3 levels reveals significant upregulation at 2 W (46.55 ± 7.31%) and 4 W (87.22 ± 11.14%) compared to control (18.86 ± 10.37%; p < 0.001). c WB showing α-smooth-muscle-actin (α-SMA) expression in the same groups. d Quantification shows reduced α-SMA expression at 2 W (52.79 ± 14.99%) and 4 W (39.16 ± 17.52%) versus control (80.94 ± 14.26%; p = 0.005 and p < 0.001, respectively).

    Techniques: Immunofluorescence, Staining, Control, Cell Characterization